Callaboration

PACR Collaborations/Discussions

1. Proteomics and Transcriptomics of Kidney Diseases, Matthias Kretzler, MD, recruited from Munich, Germany, to Dept of Internal Medicine/Nephrology. Joined PACR, Nov 2005.
2. Proteomics and Metabolomics of Diabetes Mellitus, Subramanian Pennathur, MD, PhD, recruited from the University of Washington to Dept of Internal Medicine/Nephrology. Joined PACR, February 2006.
3. Proteomics Informatics, Alexey Nesvizhskii, PhD, recruited from Institute for Systems Biology in Seattle, WA, to Dept of Pathology, PACR, and Center for Computational Medicine and Biology. Joined PACR, November, 2005.
4. Proteomics of Human Embryonic Stem Cell Neuro-differentiation, Sue O’Shea, Dept of Cell and Developmental Biology and NIH Stem Cell Center, UM. Project initiated as part of evaluation of iTRAQ technology (Andrews et al), Feb 2006.
5. Proteomics of Non-Hodgkin Lymphomas and Other Neoplasms, Kojo Elenitoba-Johnsonn, MD,PhD, and Megan Lim, MD/PhD, Dept of Pathology, University of Utah. Joined UM Dept fo Pathology, August 2006. Presentation to PACR 21 March 2007.
6. Anastasia Yocum, PhD in Pharmacology, U Penn. Joined UM as postdoctoral fellow in Proteomics (Andrews and Omenn) and Embryonic Stem Cell Biology (0’Shea) September 2006. Immediately active in PACR; research supported on Andrews sub-budget.
7. Jun-Lin Guan, PhD, Professor of Molecular Medicine, joined the UM faculty from Cornell in December 2006. Welcomed to PACR 21 February 2007. Presented research strategy on mechanisms of metastasis and roles of focal adhesion kinase at 21 March 2007 PACR mtg. Experiments using iTRAQ are being designed.
8. James Rae, PhD, Dept of Internal Medicine. Working on estrogen-receptor-positive and estrogen-receptor-negative models of breast cancer. Interest from PACR helped UM retain this highly valued faculty member when his department chair moved to another institution. Experiments using iTRAQ are being designed.
9. VadiRaja Bhat, PhD, University of Texas. Collaboration by Sreekumar et al (Aim 1, Project 1) on high throughput iTRAQ analyses.
10. Daniel Rhodes, Ph.D., and Arul Chinnaiyan, M.D., Ph.D., Compendia Biosciences, Ann Arbor, MI; use of Oncomine and Molecular Concepts Maps (especially Aim 1, Project 3).
11. Mathias Uhlen, Ph.D., Royal Institute of Technology, Stockholm, Sweden; analysis led by Rhodes and Omenn using both Oncomine (mRNA signatures) and ProteinAtlas (protein immunochemistry signatures) for the first time. (Aim 2, Project 2)
12. Sofia Merajver, M.D., Ph.D. and Alejandra Ventura, M.D., Ph.D., Division of Hematology/Oncology, Department of Internal Medicine and UM Comprehensive Cancer Center; systems analysis & modeling of breast cancer pathways (Aim 2, Project 2).
13. Leroy Hood, M.D, Ph.D., David Galas, Ph.D., and Kai Wang, Ph.D., of the Institute for Systems Biology in Seattle, and Anna Lok, M.D., F.R.C.P. of UM’s Department of Internal Medicine, Division of Gastroenterology; Hepatitis C liver cancer trials (HALT-C) for development of organ- specific signatures.
14. Rafael Isokpehi, Ph.D., Jackson State University, College of Science Engineering and Technology, and the Research Centers in Minority Institutions (RCMI), teaching and research monitoring in proteomics and proteomics informatics and statistics.
15. David Reisman, MD and Selina Glaros, MD, Hematology/Oncology, UM. Characterization of role of BRM & SWI/SNF in lung cancer.