GuanLab achieved top performance in 2013 DREAM (Dialogue for Reverse Engineering Assessments and Methods) - breast cancer network inference challenge
DCM&B Chair, Brian D. Athey, Ph.D., elected as fellow of the American College of Medical Informatics (ACMI)

PNAS paper published by Jun Li, Assistant Professor, Human Genetics and Assistant Research Professor, Computational Medicine and Bioinformatics and colleagues, on circadian rhythm disruption in depression

PNAS paper published by Jun Li, Assistant Professor, Human Genetics and Assistant Research Professor, Computational Medicine and Bioinformatics and colleagues, on circadian rhythm disruption in depression

PNAS paper published by Jun Li, Assistant Professor, Human Genetics and Assistant Research Professor, Computational Medicine and Bioinformatics and colleagues, on circadian rhythm disruption in depression.

"Every cell in our bodies runs on a 24-hour clock, tuned to the night-day, light-dark cycles that have ruled us since the dawn of humanity. The brain acts as timekeeper, keeping the cellular clock in sync with the outside world so that it can govern our appetites, sleep, moods and much more.

But new research shows that the clock may be broken in the brains of people with depression -- even at the level of the gene activity inside their brain cells.

It’s the first direct evidence of altered circadian rhythms in the brain of people with depression, and shows that they operate out of sync with the usual ingrained daily cycle. The findings, in the Proceedings of the National Academy of Sciences, come from scientists from the University of Michigan Medical School and other institutions."