GuanLab achieved top performance in 2013 DREAM (Dialogue for Reverse Engineering Assessments and Methods) - breast cancer network inference challenge

Rajasree Menon, Ph.D.

Rajasree Menon, Ph.D.

Research Investigator, Department of Computational Medicine & Bioinformatics

Phone: 

(734) 615-9720

Research: 

My main research is focused on studying alternative splice isoforms/variants that are involved in different types of human cancers. I have developed an approach to integrate transcriptomic data with mass-spectrometric data for the identification of splice isoforms. The functional role of the distinct splice variant of a gene is not well understood. I use different computational tools to understand the potential functions and interactions of these variants. I collaborate with other University of Michigan cancer specialists to experimentally validate our splice variant predictions in human normal and tumor tissue samples.

Research Area: 
Databases and Computing
Genomics
Molecular Biology
Proteomics and Metabolomics