GuanLab achieved top performance in 2013 DREAM (Dialogue for Reverse Engineering Assessments and Methods) - breast cancer network inference challenge

News & Announcements

Chih Chiang Tsou
Bioinformatics Ph.D. student Chih-Chiang Tsou from Alexey Nesvizhskii laboratory is the first author on a recently published manuscript in Nature Methods presenting a novel computational framework for data independent acquisition (DIA) proteomics. DIA mass spectrometry is a promising new technology for analyzing complex proteomics samples, highlighted as a "Method to Watch" by Nature Methods in their special “Method of the Year 2014” category. The novel computational framework and open-source computational tool DIA-Umpire developed by Chih-Chiang and co-authors allows highly efficient analysis of DIA proteomics data, addressing several key limitations of previously described data analysis strategies. DIA-Umpire should facilitate the adoption of DIA technology by the proteomic community and enable a wide range of biological applications.

49 faculty were inducted into The League of Research Excellence including 8 CCMB faculty members: Vivian Cheung, Thomas Gardner, John Moran, Gil Omenn, Maureen Sartor, Pat Schloss, and Cristen Willer, and John Younger. The League of Research Excellence was established in 2011 to recognize faculty who have made significant contributions to the Medical School's research enterprise. Membership in the League is testimony to the quality of the inductees’ research and scholarship, and is a reflection of the high regard we have for their service to the Medical School’s research mission.

DCM&B Chair, Brian Athey, Ph.D., elected to membership in the American College of Medical Informatics (ACMI)
The College originated in 1984 when five pioneers in informatics decided to establish an honorific society to recognize expertise in biomedical Informatics. Today, there are nearly 300 Fellows, with 10-20 new Fellows elected each year when Voting Fellows of the College judge nominees during a formal election process. Use the search feature below to view the names of individuals who have achieved ACMI Fellowship, one of the highest honors in the field of informatics.

University of Michigan experts in genetic and statistical analysis, Lou Gehrig's disease, head and neck cancer, health policy and nursing are among the new members of the Institute of Medicine of the National Academies, one of the highest honors in the fields of health and medicine. Gonçalo Abecasis, Dr. Carol Bradford, Dr. Eva Feldman, Dr. Mark Fendrick, Susan Murphy and Kathleen Potempa were elected to the IOM in recognition of their major contributions to the advancement of the medical sciences, health care and public health. With their election, the university now has 59 past and present members of the IOM.

"Oxidative stress in our bodies is an unavoidable consequence of breathing and eating, but when it gets out of balance, it's implicated in cancer, neurodegenerative diseases, heart disease, diabetes and aging itself. In an effort to pinpoint how and where oxidative damage begins, a chemistry professor at U-M is developing new technologies to map its effects on our cells. Brent Martin, the William R. Roush Assistant Professor of Chemistry, has received a $2.2 million Director's New Innovator grant award from the National Institutes of Health for the project. As part of NIH's "High Risk/High Reward" research programs, the New Innovator Awards support researchers doing "unusually innovative research." Martin is one of 50 researchers across the country to receive it in 2014."

"If you’ve ever doubted the inherent coolness of the diabetes community, take a look around. You’ll see entertainers, advocates, athletes, entrepreneurs, and humanitarians. You’ll find scientists, inventors, and community organizers. They climb the tallest mountains, address Congress, invent tools that make living with diabetes easier, and research for a cure. Just as remarkable are the men and women featured on the following pages. As varied as their professions may be, there’s a unifying factor: All are making lives better for people with diabetes. They’re creating a community, raising awareness and funds, working on prevention, and inspiring others with lives well lived."

The Center for the Discovery of New Medicines has awarded its third round of grants, providing funding to eight projects from labs across U-M including, CCMB faculty member, Matthew Young, Department of Pharmacology, Medical School: "A non-active site directed approach to inhibit deubiquitinases for cancer therapy" Project summary: Drive the development of optimized cancer therapeutics by determining crystal structures in the Center for Structural Biology of a novel class of enzyme targets whose up-regulation is known to drive certain cancers like leukemia.

Jun Li
The Basic Sciences Research Award recognizes a scientist or group of scientists identified as having made outstanding contributions to the Medical School in basic biomedical science research.

"Team Guan Lab contributed the winning prediction for subchallenge 1. Team GuanLab was comprised of Fan Zhu and Yuanfang Guan of the University of Michigan in the USA. There was a tie for winning submissions to subchallenge 2 between Team GuanLab and Team SBI_Lab. Team SBI_Lab was comprised of Javier Garcia-Garcia, Daniel Aguilar, Jaume Bonet, Daniel Poglayen, Oriol Fornes, Emre Guney, Joan Planas-Iglesias, Manuel Alejandro Marin, Bernat Anton, and Baldo Oliva of the Unversitat Pompeu Fabra in Spain. In addition, eight teams have been selected based on performance to participate in the Community Phase. These include: Team GuanLab, Team SBI_Lab, Team Lucia, teamMI, Team STSI, Team Linked Open Data, Team Outliers, and the UTSW team."