The mission of the Department of Computational Medicine and Bioinformatics (DCM&B) is to create novel and impactful informatics and computationally-based methods, tools, and algorithms, and resources to extend basic and clinical research capabilities and results. Computational medicine and bioinformatics is an applied field, and relies on an interdisciplinary research culture for success. DCM&B is deeply committed to training the next generation of innovators and leaders in this field, applying to create new science, translational research, and creating new methods to improve public health and societal welfare.
Chair, Department of Computational Medicine and Bioinformatics
Brian D. Athey, Ph.D. (Professor DCM&B)
Director, CCMB
Gilbert S. Omenn, M.D., Ph.D. (Professor of Internal Medicine, Molecular Medicine & Genetics; Human Genetics; Public Health; Research Professor, DCM&B)
Associate Director, CCMB
H. V. Jagadish, Ph.D. (Bernard A. Galler Collegiate Professor of Electrical Engineering & Computer Science)
Co-Directors, Bioinformatics Graduate Program
Margit Burmeister, Ph.D. (Psychiatry); Research Professor, DCM&B
Daniel M. Burns, Jr., Ph.D. (Professor of Mathematics, LS&A)
Director, Bioinformatics Core
James D. Cavalcoli, Ph.D. (Research Investigator, DCM&B)
Chief Department Administrator
Linda Peasley
DCM&B Faculty are passionate contributors to various aspects of the field, whose experience is diverse and spans the bioinformatics and clinical research continuum. Many are national leaders in their subdisciplines.
Core DCM&B Instruction Faculty:
Brian D. Athey, Ph.D.
Jeffrey de Wet, Ph.D.
Barry Grant, Ph.D.
Ryan Mills, Ph.D.
Gilbert S. Omenn, M.D., Ph.D.
Indika Rajapakse, Ph.D.
Yang Zhang, Ph.D.
Core DCM&B Research Faculty:
Jim Cavalcoli, Ph.D.
Yuanfang Guan, Ph.D.
Alla Karnovsky, Ph.D.
Richard C. McEachin, Ph.D.
Rajasree Menon, Ph.D.
Maureen Sartor, Ph.D.
Adjunct DCM&B Faculty:
CCMB Affiliated Faculty with Secondary Appointments in DCM&B
Phil Andrews, Ph.D. (Biological Chemistry); Research Professor, DCM&B
Margit Burmeister, Ph.D.(Psychiatry); Research Professor, DCM&B
Daniel Forger, Ph.D. (Mathematics, LS&A); Research Assistant Professor, DCM&B
Jeff Kidd, Ph.D.(Human Genetics); Research Assistant Professor, DCM&B
Matthias Kretzler, M.D. (Internal Medicine, Nephrology); Research Professor, DCM&B
Jun Li, Ph.D. (Human Genetics); Assistant Research Professor, DCM&B
Alexey Nesvizhskii, Ph.D. (Pathology); Associate Professor, DCM&B
Mercedes Pascual, Ph.D. (EEB, LS&A); Research Professor, DCM&B
Santiago Schnell, Ph.D. (Molecular & Integrative Physiology); Associate Research Professor, DCM&B
Elizabeth Speliotes, M.D., Ph.D., M.P.H. (Internal Medicine, Gastrointestinal); Assistant Professor, DCM&B
Jeremy Taylor, Ph.D.(Biostatistics, Public Health); Research Professor, DCM&B
Cristen Willer, Ph.D. (Internal Medicine, Cardiovascular Medicine); Assistant Professor, DCM&B
The Bioinformatics Graduate Program (BGP) is the academic component of DCM&B. The BGP is led by Dr. Margit Burmeister, Professor of Psychiatry & Human Genetics and Dr. Daniel M Burns, Jr., Professor of Mathematics. Multidisciplinary faculty support the robust curriculum and research opportunities for the students.
The Bioinformatics Graduate Program is also home to two training grants: The Bioinformatics Training Program and The Proteome Informatics of Cancer Training Program.
A faculty handbook outlines the responsibilities of faculty mentoring Bioinformatics Ph.D. students as they proceed through their student career. As always, specific questions and commentary can be addressed to the Program directors.
The U-M Center for Computational Medicine and Bioinformatics (CCMB) is a campus-wide interdisciplinary academic center with over 100 affiliated faculty members. The faculty membership of CCMB has a strong representation from diverse fields such as mathematics, computer science, and statistics, and is complemented by faculty with biological and biomedical expertise who are applying cutting-edge biomedical informatics to their work. CCMB is the University of Michigan institutional leader in the entire spectrum of biomedical informatics disciplines, including bioinformatics, clinical informatics, and health informatics.
The Bioinformatics Core is jointly supported by the Department of Computational Medicine and Bioinformatics and the U-M Medical School Office of Research as part of the Biomedical Research Core Facilities (BRCF). The Bioinformatics Core is a team of bioinformatics analysts, and software developers dedicated to providing bioinformatics analysis, application development and data infrastructure support for researchers in the U-M Medical School and across the University of Michigan
The National Center for Integrative Biomedical Informatics (NCIBI) was founded in 2005 as one of seven National Centers for Biomedical Computing (NCBC) within the NIH Roadmap. By integrating vast amounts of diverse, multi-scale data, NCIBI develops and disseminates tools for molecular biomedical research from a systems biology perspective. This center is led by Dr. Brian Athey
The tranSMART Foundation was established in 2013, and is a public-private partnership – the result of collaborations between scientists in the United States and the European Union. Founding partners include the University of Michigan, the Pistoia Alliance and Imperial College London. The tranSMART Foundation enables effective sharing, integration, standardization and analysis of heterogeneous data from collaborative translational research by mobilizing the tranSMART open-source software and open-data community. The foundation is led by Co-CEO's Dr. Brian Athey and Dr. Michael Braxenthaler.